Table of Contents

Executive Summary 4
Understanding Genomics 5
What is Genomics? 5
Historical Background 5
Importance of Bacteriophage Genomics 6
Importance of Cyanobacteria Genomics 6
Genomics & Implications of the Human Genome Project 7
Potential Medical Benefits 7
Privacy and Fair Use of Genetic Information 7
Intellectual Property 7
Ethical Implications 8
Social Implications 8

Understanding Proteomics 9
What is Proteomics?9
Study of Proteomics 10
Importance of Biomarkers 11
Segments of Proteomics 12
Proteomics Processes 13
Protein Separation 13
Protein Detection 13
Protein Identification 14
Pattern Analysis and Interpretation 14
Various Technologies Used 14

Introduction to Drug Discovery 16
Overview 16
Development Process 16
Basic Research Stage (Years 0-3) 16
Preclinical Testing (Years-4-6) 16
Phase I (Years 7-10) 16
Phase II (Years 7-10) 17
Phase III (Years 7-10) 17
Regulatory Approval 17
New Drug 17

Role of Technologies in Drug Discovery 18
Better Understanding of the Process and Mechanisms 18
Intelligently Analyzing the Data 18
Focus on Experiments that are Likely to Succeed 18
Reduction of Data Processing Costs 19

Drug Discovery & Processes Involved 20
Genomics in Drug Discovery 20
Proteomics in Drug Discovery 21
Profiling Proteomics 21
Functional Proteomics 22
Structural Proteomics 22

Future Outlook for the Drug Discovery Market 23

Glossary 24